Vitargent (International) Biotechnology Limited serves as a platform of innovative testing methods


Transgenic medaka (Oryzias Melastigma)

Transgenic medaka is designed for testing Estrogenic Endocrine Disruptors (EEDs), a major group of harmful substances. It can be used to test everyday consumer products (including food, pharmaceuticals and cosmetics), and monitor the aquatic environment. Transgenic medaka fish assay is so far the most accurate and cost-effective method to detect Estrogenic Endocrine Disruptors (EEDs). When the fish detect EEDs, it will produce green fluorescence (see the picture on the right), and then the intensity of the light is used to quantify the EEDs. By applying this technology in the screening stage of the testing process, 60% of the time and money can be saved, while it can also detect unknown substances belonging to the group of EEDs.


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Transgenic medaka produces green
fluorescence light


Zebrafish (Danio rerio)

Zebrafish and zebrafish embryo test is designed for testing samples’ toxicity, including general toxicity, target organs, and the toxicity mechanism. Zebrafish bioassay can be applied to various situations, including drug development, waste water monitoring, etc. Zebrafish models mimic human metabolic system, so that we can use these models to predict the possible toxic effect of the testing samples to not only fish, but human beings as well.



Adult zebrafish